Saturday 8 April 2017

2-OriginofOrganic

Question : What is the origin of the term organic chemistry?
a) Prior to 1828, most carbon compounds had been found only in living matter and it was believed that their natural synthesis required vital force. In that year, Friedrich Wohler created Urea from ammonium isocyanate and the definitions of organic and inorganic chemistry changed.
b) There is no such thing as vital force theory. Organic chemistry was ever since the beginning considered the study of special carbon compounds.
c) The substances not obtained from organs are all inorganic. Rest of the compounds are organic.
d) None of these
Answer a) is the best fit answer
Explaination
Before the nineteenth century, chemists generally believed that compounds obtained from living organisms were endowed with a vital force that distinguished them from inorganic compounds. According to the concept of vitalism (vital force theory), organic matter was endowed with a "vital force". During the first half of the nineteenth century, some of the first systematic studies of organic compounds were reported. Around 1816 Michel Chevreul started a study of soaps made from various fats and alkalis. He separated the different acids that, in combination with the alkali, produced the soap. Since these were all individual compounds, he demonstrated that it was possible to make a chemical change in various fats (which traditionally come from organic sources), producing new compounds, without "vital force". In 1828 Friedrich Wöhler produced the organic chemical urea (carbamide), a constituent of urine, from the inorganic ammonium cyanate NH4CNO, in what is now called the Wöhler synthesis. Although Wöhler was always cautious about claiming that he had disproved the theory of vital force, this event has often been thought of as a turning point.
In 1856 William Henry Perkin, while trying to manufacture quinine, accidentally manufactured the organic dye now known as Perkin’s mauve. Through its great financial success, this discovery greatly increased interest in organic chemistry.
The crucial breakthrough for organic chemistry was the concept of chemical structure, developed independently and simultaneously by Friedrich August Kekulé and Archibald Scott Couper in 1858.Both men suggested that tetravalent carbon atoms could link to each other to form a carbon lattice, and that the detailed patterns of atomic bonding could be discerned by skillful interpretations of appropriate chemical reactions.
The pharmaceutical industry began in the last decade of the 19th century when the manufacturing of acetylsalicylic acid—more commonly referred to as aspirin—in Germany was started by Bayer. The first time a drug was systematically improved was with arsphenamine (Salvarsan). Though numerous derivatives of the dangerous toxic atoxyl were examined by Paul Ehrlich and his group, the compound with best effectiveness and toxicity characteristics was selected for production.

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